Optically Computed Phase Microscopy for High‑Contrast, Label‑Free Imaging (Optically Computed Phase Microscopy, Tech ID: 22‑004)
Technology Overview: This technology enables optically computed phase microscopy, allowing high‑contrast, quantitative imaging of transparent samples without fluorescent labels. By computationally extracting phase information directly from optical signals, the system reveals structural and morphological details that are otherwise difficult to visualize using conventional bright‑field microscopy. The approach supports real‑time imaging with reduced hardware complexity, making it attractive for both research and clinical diagnostic settings.
Industry Pain Point: Traditional phase‑contrast imaging systems require complex optics or labeling that adds cost and complexity.
NJIT Solution: This method provides label‑free, quantitative phase imaging using optically computed processing.
Key Features & Advantages
- Label‑free, high‑contrast imaging
- Quantitative phase information
- Reduced optical system complexity
- Suitable for biological and material samples
Development Stage: TRL 4–5 – Laboratory validation demonstrated.
Target Markets
- Biomedical imaging and diagnostics
- Cell biology research
- Microscopy instrument manufacturers
Market Opportunity
- Global microscopy market (2026): ~$10B
- CAGR: ~7–8%
- Projected market size (2035): ~$18–20B
Commercial & IP Details
Inventors: Xuan Liu, Yuwei Liu, Zhaoxiong Wan, Yuanwei Zhang