Electrochemical Mass Spectrometry Platform for Precise Relative Quantitation (Relative Quantitation Using Electrochemical Mass Spectrometry, Tech ID: 20‑016)
Technology Overview: This technology integrates electrochemical modulation with mass spectrometry to enable precise relative quantitation of chemical species. By electrochemically controlling analyte generation or transformation prior to mass analysis, the platform improves selectivity and quantitative accuracy. The approach reduces matrix effects and eliminates the need for complex internal standards, making it particularly valuable for complex chemical, biological, and pharmaceutical samples.
Industry Pain Point: Conventional mass spectrometry struggles with quantitative consistency across complex sample matrices.
NJIT Solution: Electrochemical control enables more reliable relative quantitation without extensive sample preparation.
Key Features & Advantages
- Enhanced quantitative reproducibility
- Reduced dependence on internal standards
- Improved selectivity in complex samples
- Compatible with existing MS systems
Development Stage: TRL 4–5 – Laboratory validation demonstrated.
Target Markets
- Pharmaceutical analytical development
- Bioanalytical testing
- Environmental and chemical analysis
Market Opportunity
- Global analytical instrumentation market (2026): ~$75B
- CAGR: ~6–7%
- Projected market size (2035): ~$125–135B
Commercial & IP Details
Inventors: Hao Chen, Pengyi Zhao