Hydrophilic Functional Particle Platform for Enhanced Delivery of Hydrophobic Drugs | New Jersey Institute of Technology

Hydrophilic Functional Particle Platform for Enhanced Delivery of Hydrophobic Drugs

Hydrophilic Functional Particle Platform for Enhanced Delivery of Hydrophobic Drugs (Hydrophilic Functional Particles in the Delivery of Hydrophobic Drugs, Tech ID: 21‑002)

Technology Overview: This technology enables hydrophilic functionalized particles that improve solubility, dispersion, and bioavailability of hydrophobic drugs. By engineering particle surfaces to interact favorably with aqueous environments, the platform mitigates one of the most persistent challenges in pharmaceutical development. The technology is adaptable to multiple drug classes and is compatible with conventional formulation workflows.

Industry Pain Point: Poor aqueous solubility limits bioavailability and clinical success of many drug candidates.

NJIT Solution: These particles enable efficient aqueous delivery of hydrophobic drugs, improving therapeutic potential without complex reformulation.

Key Features & Advantages

  • Enhanced dispersion of hydrophobic compounds
  • Improved bioavailability
  • Scalable particle engineering approach
  • Compatible with standard pharmaceutical processes

Development Stage: TRL 3–4 – Laboratory validation demonstrated.

Target Markets

  • Oral and injectable drug formulations
  • Specialty and generic pharmaceuticals
  • Drug delivery platform developers

Market Opportunity

  • Global drug delivery systems market (2026): ~$65B
  • CAGR: ~7–8%
  • Projected market size (2035): ~$120–130B

Commercial & IP Details

Inventors: Mohammad Islam, Somenath Mitra

Patent Information:
Category(s):
Drug Delivery, Excipients & Biopharma Manufacturing
For Information, Contact:
Ikechukwu Nwabufo
IP Licensing & Marketing Manager
in49@njit.edu
Inventors:
Somenath Mitra
Mohammad Islam
Keywords:
Aqueous Delivery
Bioavailability
Drug Delivery
Drug Discovery Technologies
Hydrophobic Drugs
Patent Pending
Pharmaceutical Processing
Pharmaceuticals
Specialty Drug Manufacture