Continuous Anti‑Solvent Crystallization Platform for Uniform Polymer‑Coated Nanoparticles (Porous Hollow Fiber Anti‑Solvent Crystallization‑Based Continuous Method of Polymer Coating on Submicron and Nanoparticles, Tech ID: 14‑036)
Technology Overview: This technology enables continuous polymer coating of submicron and nanoparticles using a porous hollow‑fiber anti‑solvent crystallization process. The system allows precise control of coating formation through regulated mass transfer across hollow fiber membranes, producing uniform and reproducible polymer layers. Compared to batch methods, this approach improves scalability, consistency, and process efficiency. It is particularly well suited for pharmaceutical, chemical, and advanced material formulations requiring tightly controlled particle surface properties.
Industry Pain Point: Existing nanoparticle coating methods struggle with scalability, reproducibility, and batch‑to‑batch variability.
NJIT Solution: This platform enables continuous, membrane‑controlled crystallization, delivering uniform coatings at industrially relevant scales.
Key Features & Advantages
- Continuous coating of nano‑ and submicron particles
- Precise control over coating thickness
- Scalable, manufacturing‑friendly platform
- Reduced process variability versus batch methods
Development Stage: TRL 5–6 – Laboratory and pilot‑scale demonstration completed.
Target Markets
- Pharmaceutical formulations
- Specialty chemicals
- Advanced particulate materials
Market Opportunity
- Global nanoparticle processing market (2026): ~$12B
- CAGR: ~9–10%
- Projected market size (2035): ~$26–28B
Commercial & IP Details
Inventors: Dengyue Chen, Robert Pfeffer, Dhananjay Singh, Kamalesh Sirkar