Intellectual Property and Technology Licensing Office (IPTLO)

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Pyroptosis‑Triggering Lipid Nanoparticles for Targeted Immunogenic Cell Death
Technology Overview: This technology introduces lipid nanoparticle (LNP) formulations engineered to trigger pyroptosis, an immunogenic form of programmed cell death. By delivering payloads that selectively activate pyroptotic pathways, the platform enables localized cell destruction while stimulating innate immune responses. The technology is adaptable...
Innovator(s) Fengqiao Li, Xiaoyang Xu, William Ho
Keywords(s): Cancer, Combination Therapy, Immuno-oncology, Immunotherapies, Inflammatory Disease Modulation, LNP Manufacturing, Patent Pending, Targeted Drug Delivery
Category(s): Drug Delivery, Excipients & Biopharma Manufacturing
Gene Delivery Platform for the Prevention and Treatment of Hair Loss
Technology Overview: This technology provides a gene delivery platform targeting hair follicles to address hair loss conditions such as androgenetic alopecia. The system enables localized delivery of genetic material that modulates biological pathways associated with hair growth and follicle regeneration. By targeting the root biological causes of hair...
Innovator(s) Xiaoyang Xu, William Ho, Zhongyu Li
Keywords(s): Aesthetic Medicine, Dermatology, Gene Therapy, Gene-Based Cosmetic Treatment, Hair Restoration, Patent Pending
Category(s): Drug Delivery, Excipients & Biopharma Manufacturing
Amino Alcohol Ionizable Lipids for Next Generation Nucleic Acid Delivery
Technology Overview: This technology introduces a novel class of amino‑alcohol‑based ionizable lipids designed to improve the delivery of nucleic acids, including mRNA and siRNA. The lipids exhibit pH‑responsive ionization, enabling efficient endosomal escape while maintaining low toxicity under physiological conditions. Their chemical tunability allows...
Innovator(s) Xiaoyang Xu, Zhongyu Li
Keywords(s): Gene Therapy, LNP Manufacturing, mRNA Therapeutics, Patent Pending, siRNA, Vaccine Delivery
Category(s): Drug Delivery, Excipients & Biopharma Manufacturing
Long‑Acting Injectable Anesthetic Formulations for Severe and Pathological Pain
Injectable Formulations of Anesthetics for any Pathological Pain Technology Overview: This NJIT technology provides injectable anesthetic formulations engineered for extended analgesia in severe or pathological pain conditions. By optimizing drug composition and release kinetics, the formulation maintains therapeutic levels over clinically meaningful...
Innovator(s) Xiaoyang Xu, Yuanxiang Tao, He Zhu
Keywords(s): Anesthetic Formulations, Cancer Pain, Extended Analgesia, Injectable, Interventional Pain Management, Neuropathic Pain, Patent Issued, Reducing Pain
Category(s): Drug Delivery, Excipients & Biopharma Manufacturing, Sustainable Systems > Nanotechnologies, Material & Chemical Processes
Photoluminescent Hydrogel Platform for Bioimaging and Therapeutic Applications
Technology Overview: This NJIT technology is a photoluminescent hydrogel that combines soft, biocompatible polymer networks with intrinsic light‑emitting properties. The hydrogel can be engineered to emit fluorescence under specific excitation wavelengths while maintaining favorable mechanical and biological characteristics. Its formulation supports...
Innovator(s) Yunghao Tsou, Xiaoyang Xu
Keywords(s): Biocompatible, Biomedical, Hydrogel, Medical Imaging, Patent Issued, Photoluminescence, Sensor, Tissue Engineering
Category(s): Biomaterials & Regenerative Therapies, Life Science & Engineering > Diagnosis & Therapeutics